Luke Hanna BSc(Hons) MBBS MRCP)

United Kingdom
Written By AB

About

Luke is a Gastroenterology trainee whose research focuses on the immunological mechanisms and cellular interactions underlying perianal Crohn’s disease. He was awarded the Imperial College London Lee Family Faculty of Medicine Scholarship in 2023 and is currently undertaking a PhD with Professor Ailsa Hart and Mr Phil Tozer at St Mark’s Hospital, in collaboration with Professor Nicholas Powell at Imperial College London. He has contributed to TOpClass projects developing clinical criteria to identify isolated perianal Crohn’s disease, as well as projects aimed at optimising combined medical and surgical therapies for fistulating disease.

 

Related Articles & Publications

Publications and Events
Defining Radiological Healing in Perianal Fistulizing Crohn's Disease: A TOpClass Global Expert Delphi Consensus
Publications
Defining Radiological Healing in Perianal Fistulizing Crohn's Disease: A TOpClass Global Expert Delphi Consensus
Publications

A global expert consensus defining what constitutes radiological healing and improvement on MRI in perianal Crohn’s disease, establishing clear, standardised criteria to guide both clinical assessment and research outcomes.

Publications
Perianal Fistulising Crohn’s Disease – Associated anorectal and fistula cancers: Systematic Review and Expert Consensus 
Publications
Perianal Fistulising Crohn’s Disease – Associated anorectal and fistula cancers: Systematic Review and Expert Consensus 
Publications

A global TOpClass review and expert consensus outlining the small but significant risk of anorectal and fistula-associated cancers in long-standing perianal Crohn’s disease, with practical guidance on risk awareness and prompt investigation of new or changing perianal symptoms.

Publications
TOpClass Consortium Meeting at ECCO 2026 
Upcoming Events
TOpClass Consortium Meeting at ECCO 2026 
Upcoming Events

TOpClass Consortium Meeting at ECCO on 19th February 2026 – click for further information. (after click, it should take them to the upcoming events tab) 

Upcoming Events

Related Research Groups

Consortium Members
The Fistula Research Unit at St. Mark’s Hospital
Europe
The Fistula Research Unit at St. Mark’s Hospital
Europe

City: London | Country: United Kingdom
The Fistula Research Unit at St. Mark’s Hospital is headed by Professor Ailsa Hart and Mr Phil Tozer. The centre has a strong history of championing research in the field of perianal Crohn’s Disease and progressing the medical and surgical management of perianal fistula. 

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Kinga Skowron Olortegui, MD